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Vancomycin data simulated with the "pkvancothomson" model.

Usage

nm_vanco

Format

A NONMEM-style data frame with 80 rows and 11 columns:

ID

Patient ID.

TIME

The recorded times of dosing events and/or observations.

CMT

Dose compartment.

DV

The dependent variable or observed concentration.

AMT

Dose administered for dosing record.

EVID

Event ID (0 = observation, 1 = dose, 2 = other, 3 = reset, 4 = reset + dose).

MDV

Missing DV (0 = not missing, 1 = missing).

RATE

Rate of drug infusion.

WT

Patient weight at TIME of measurement.

CRCL

Patient creatinine clearance at TIME of measurement.

CL_HEMO

Additional clearance attributable to hemodialysis.

References

Thomson et al. J Antimicrob Chemotherap. 2009. https://doi.org/10.1093/jac/dkp085