Busulfan data simulated with the "pkbusulfanshukla" model.

nm_busulfan

Format

A NONMEM-style data frame with 240 rows and 13 columns:

ID

Patient ID.

TIME

The recorded times of dosing events and/or observations.

CMT

Dose compartment.

DV

The dependent variable or observed concentration.

AMT

Dose administered for dosing record.

EVID

Event ID (0 = observation, 1 = dose, 2 = other, 3 = reset, 4 = reset + dose).

MDV

Missing DV (0 = not missing, 1 = missing).

RATE

Rate of drug infusion.

AGE

Patient age at TIME of measurement.

WT

Patient weight at TIME of measurement.

HT

Patient height at TIME of measurement.

SEX

Patient sex (0 = female, 1 = male).

REGI

Regimen type.

References

Shukla et al. Front Pharmacol. 2020. https://doi.org/10.3389/fphar.2020.00888