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Calculate some basic PK variables from simulated or observed data

Source: R/run_sim.R
calc_pk_variables.Rd

Calculate some basic PK variables from simulated or observed data

Usage

calc_pk_variables(data, regimen = NULL, dictionary = NULL)

Arguments

data

data.frame in NONMEM format

regimen

if specified, will replace the regimens for each subject with a custom regimen. Can be specified in two ways. The simplest way is to just specify a list with elements dose, interval, n, and route (and t_inf / rate for infusions). E.g. regimen = list(dose = 500, interval = 12, n = 5, route = "oral"). Alternatively, regimens can be specified as a data.frame. The data.frame specified all dosing times (dose, time columns) and route and t_inf / rate. The data.frame may also optionally contain a regimen column that specifies a name for the regimen. This can be used to simulate multiple regimens.

Value

data.frame