Convert dose to expected AUCinf or AUCt for 1 compartment linear PK model — dose2auc • clinPK

Convert dose to expected AUCinf or AUCt for 1 compartment linear PK model

Usage

dose2auc(dose, CL, V, t_auc = NULL)

Arguments

dose: dose amount
CL: Clearance
V: Volume of distribution
t_auc: if AUC_t is desired, `t_auc` specifies time until which AUC_t is calculated

Examples

dose2auc(dose = 1000, CL = 5, V = 50)
#> [1] 200
dose2auc(dose = 1000, CL = 5, V = 50, t_auc = c(12, 24, 48, 72))
#> [1] 139.7612 181.8564 198.3541 199.8507