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clinPK 0.14.0

Major changes

  • Refactored pct_*_for_*() functions. As input, they now accept vectors of values. They now return either a vector of percentiles for the given physical measurement, or a data frame with the observed percentile for the given physical measurement, along with a select distribution of physical measurements at particular percentiles. These functions also use updated CDC growth charts instead of WHO growth charts.
  • Added median_*_for_*() functions for calculating median growth values for infants and children. These functions replace the now-deprecated return_median argument in the pct_*_for_*() functions.
  • Added CDC growth chart data sets as package data (see ?"growth-charts").
  • Removed read_who_table() function, as part of the refactor for the pct_*_for_*() functions.

Minor updates

  • Activated roxygen’s markdown parser for improved function documentation

clinPK 0.13.0

CRAN release: 2024-02-23

Major changes

  • Added support for converting bilirubin and albumin units
  • Added support for Calvert equation for carboplatin
  • Added function for grading neutropenia

Minor updates

  • Added support for Hoek eGFR method
  • Vectorize weight2kg() over both units and values

clinPK 0.11.1

CRAN release: 2022-05-09

Major changes

  • various corrections in nca() function
  • various updates to AKI staging equations: MDRD equation (use 2006 publication), kDIGO and PRIFLE
  • added equations of MDRD and CKD-EPI without race

Minor updates

  • refactor of calc_ibw()
  • fixed Boyd equation in calc_bsa()
  • added function to convert flow units
  • updates to 2-sample equation
  • added Cockcroft-Gault equation for spinal cord injury patients
  • consistent handling of missing/unrecognized data in calc_ibw()/calc_ffm()/calc_egfr()
  • various minor fixes and updates
  • various documentation updates
  • added many unit tests, increase overall coverage to >86%

clinPK 0.9.0

CRAN release: 2017-06-19

Initial CRAN version.