Concentration predictions for 1-compartmental PK model after single or multiple bolus doses
Source:R/pk_1cmt_bolus.R
pk_1cmt_bolus.Rd
Concentration predictions for 1-compartmental PK model after single or multiple bolus doses
Usage
pk_1cmt_bolus(t = c(0:24), dose = 100, tau = 12, CL = 3, V = 30, ruv = NULL)
Examples
pk_1cmt_bolus(dose = 500, tau = 12, CL = 5, V = 50)
#> t dv
#> 1 0 10.000000
#> 2 1 9.048374
#> 3 2 8.187308
#> 4 3 7.408182
#> 5 4 6.703200
#> 6 5 6.065307
#> 7 6 5.488116
#> 8 7 4.965853
#> 9 8 4.493290
#> 10 9 4.065697
#> 11 10 3.678794
#> 12 11 3.328711
#> 13 12 13.011942
#> 14 13 11.773692
#> 15 14 10.653277
#> 16 15 9.639484
#> 17 16 8.722166
#> 18 17 7.892142
#> 19 18 7.141105
#> 20 19 6.461539
#> 21 20 5.846642
#> 22 21 5.290261
#> 23 22 4.786826
#> 24 23 4.331299
#> 25 24 13.919122
pk_1cmt_bolus(dose = 500, tau = 12, CL = 5, V = 50, t = 24)
#> t dv
#> 1 24 13.91912
pk_1cmt_bolus(
dose = 500, tau = 12, CL = 5, V = 50,
ruv = list(prop = 0.1, add = 0.1))
#> t dv
#> 1 0 8.590212
#> 2 1 9.185810
#> 3 2 6.190250
#> 4 3 7.321376
#> 5 4 6.968600
#> 6 5 6.855390
#> 7 6 4.505930
#> 8 7 4.867403
#> 9 8 4.545919
#> 10 9 3.961961
#> 11 10 3.461700
#> 12 11 3.347072
#> 13 12 15.671017
#> 14 13 9.822071
#> 15 14 11.305911
#> 16 15 7.850640
#> 17 16 8.202945
#> 18 17 7.845631
#> 19 18 7.503716
#> 20 19 5.915386
#> 21 20 6.395897
#> 22 21 5.486925
#> 23 22 4.220135
#> 24 23 4.662672
#> 25 24 16.356583