Cmin (trough) for linear 1-compartment PK model at steady state, bolus dosing

Takes single values for dose or model parameters, or vector of either dose or parameters (but not both).

Usage

pk_1cmt_bolus_cmin_ss(dose = 100, tau = 12, CL = 3, V = 30, ruv = NULL)

Arguments

dose

dose

tau

dosing interval

CL

clearance

V

volume of distrubition

ruv

residual variability, specified as list with optional arguments for proportional, additive, or exponential components, e.g. `list(prop=0.1, add=1, exp=0)`

Examples

pk_1cmt_bolus_cmin_ss(
  dose = 500, tau = 12, CL = 5, V = 50)
#> [1] 4.310128