Concentration predictions for 1-compartmental PK model with bolus dosing at steady state
Source:R/pk_1cmt_bolus_ss.R
pk_1cmt_bolus_ss.Rd
Concentration predictions for 1-compartmental PK model with bolus dosing at steady state
Usage
pk_1cmt_bolus_ss(t = c(0:24), dose = 100, tau = 12, CL = 3, V = 30, ruv = NULL)
Examples
pk_1cmt_bolus_ss(dose = 500, tau = 12, CL = 5, V = 50)
#> t dv
#> 1 0 14.310128
#> 2 1 12.948339
#> 3 2 11.716142
#> 4 3 10.601203
#> 5 4 9.592365
#> 6 5 8.679531
#> 7 6 7.853565
#> 8 7 7.106199
#> 9 8 6.429955
#> 10 9 5.818064
#> 11 10 5.264402
#> 12 11 4.763428
#> 13 12 14.310128
#> 14 13 12.948339
#> 15 14 11.716142
#> 16 15 10.601203
#> 17 16 9.592365
#> 18 17 8.679531
#> 19 18 7.853565
#> 20 19 7.106199
#> 21 20 6.429955
#> 22 21 5.818064
#> 23 22 5.264402
#> 24 23 4.763428
#> 25 24 14.310128
pk_1cmt_bolus_ss(
dose = 500, tau = 12, CL = 5, V = 50,
ruv = list(prop = 0.1, add = 0.1))
#> t dv
#> 1 0 15.596175
#> 2 1 12.694063
#> 3 2 11.463693
#> 4 3 10.638752
#> 5 4 9.611688
#> 6 5 9.349190
#> 7 6 6.197413
#> 8 7 9.087357
#> 9 8 6.253314
#> 10 9 5.887370
#> 11 10 5.941034
#> 12 11 4.185384
#> 13 12 15.888638
#> 14 13 12.673333
#> 15 14 10.298297
#> 16 15 9.609103
#> 17 16 10.720317
#> 18 17 8.898686
#> 19 18 8.233502
#> 20 19 5.947151
#> 21 20 5.651566
#> 22 21 5.947948
#> 23 22 6.063056
#> 24 23 5.007859
#> 25 24 16.166958