Calculate dose to achieve steady state trough for 1-compartmental PK model with infusion dosing at steady state

Calculate dose to achieve steady state trough for 1-compartmental PK model with infusion dosing at steady state

Usage

pk_1cmt_inf_dose_from_cmin(cmin = 1, tau = 12, t_inf = 1, CL = 3, V = 30)

Arguments

cmin

desired trough concentration

tau

dosing interval

t_inf

infusion time

CL

clearance

V

volume of distribution

Examples

dos <- pk_1cmt_inf_dose_from_cmin(
  cmin = 20, tau = 12, t_inf = 2,
  CL = 5, V = 50)
find_nearest_dose(dos, 100)
#> [1] 2100