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Cmin (trough) for 2-compartmental PK model, bolus dosing at steady state

Usage

pk_2cmt_bolus_cmin_ss(
  dose = 100,
  tau = 12,
  CL = 3,
  V = 30,
  Q = 2,
  V2 = 20,
  ruv = NULL
)

Arguments

dose

dose

tau

dosing interval

CL

clearance

V

volume of central compartment

Q

inter-compartimental clearance

V2

volume of peripheral compartment

ruv

residual error (list)

Examples

pk_2cmt_bolus_cmin_ss(dose = 1000, tau = 12, CL = 5, V = 50, Q = 20, V2 = 200)
#> [1] 12.82731