Core function to simulate a single subject

Core function to simulate a single subject

Usage

sim_subject(data, cov_mapping, pars_true_i, design, verbose = FALSE, ...)

Arguments

data

data for subject

cov_mapping

a named vector indicating correspondence between model covariates and data frame columns. Vector names should reflect all covariates defined by the model, and vector values should represent the associated column in the provided data set.

pars_true_i

PK parameters for the individual. See generate_iiv.

design

trial design, created using create_trial_design()

verbose

verbose output?

...

arguments passed on to simulate_fit or dose_optimization_method function.